c2-m1: the frequency of revertant colored versus colorless derivatives (cont.)

In a previous report (MNL 60), the discrepancy between the frequency of colored vs. colorless derivatives of this allele was described. With the revelation that the Spm of this autonomously mutating allele lies in the promoter region support is provided that excisions in the promoter region are such that colored derivatives are more likely than colorless. This would indicate that possibly excisions leading to base pair alterations in the promoter region are more likely to be tolerated and thus yield wild type products despite a change in the fidelity of the gene sequence as opposed to those changes in the structural part of the C2 gene.

Peter A. Peterson


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